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Tumor cell senescence response produces aggressive variants

Tumors often respond favorably to initial chemotherapy but eventually relapse with drug resistance and increased metastatic potential. Cellular senescence is a major therapeutic outcome of cancer chemotherapy, which leads to tumor stasis or regression through immune clearance of senescent cells. How...

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Detalles Bibliográficos
Autores principales:	Yang, Leixiang, Fang, Jia, Chen, Jiandong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5563524/ https://www.ncbi.nlm.nih.gov/pubmed/28845296 http://dx.doi.org/10.1038/cddiscovery.2017.49

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