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Atorvastatin enhances radiosensitivity in hypoxia-induced prostate cancer cells related with HIF-1α inhibition

Hypoxia could enhance radioresistance in prostate cancer cells through up-regulating HIF-1α, which could be inhibited by statins in several cancer cells. However, this effect of statins in prostate cancer remains unclear. In the present study, we aim to investigate the effect of atorvastatin on HIF-...

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Detalles Bibliográficos
Autores principales: Chen, Bin, Zhang, Minguang, Xing, Dongwei, Feng, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5563539/
https://www.ncbi.nlm.nih.gov/pubmed/28760843
http://dx.doi.org/10.1042/BSR20170340