Inhibition of Host Cell Lysosome Spreading by Trypanosoma cruzi Metacyclic Stage-Specific Surface Molecule gp90 Downregulates Parasite Invasion

Successful infection by Trypanosoma cruzi, the agent of Chagas' disease, is critically dependent on host cell invasion by metacyclic trypomastigote (MT) forms. Two main metacyclic stage-specific surface molecules, gp82 and gp90, play determinant roles in target cell invasion in vitro and in ora...

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Detalles Bibliográficos
Autores principales: Rodrigues, João Paulo Ferreira, Sant'ana, Guilherme Hideki Takahashi, Juliano, Maria Aparecida, Yoshida, Nobuko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2017
Materias:
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5563561/
https://www.ncbi.nlm.nih.gov/pubmed/28607099
http://dx.doi.org/10.1128/IAI.00302-17

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5563561/
https://www.ncbi.nlm.nih.gov/pubmed/28607099
http://dx.doi.org/10.1128/IAI.00302-17

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