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Inhibition of Host Cell Lysosome Spreading by Trypanosoma cruzi Metacyclic Stage-Specific Surface Molecule gp90 Downregulates Parasite Invasion
Successful infection by Trypanosoma cruzi, the agent of Chagas' disease, is critically dependent on host cell invasion by metacyclic trypomastigote (MT) forms. Two main metacyclic stage-specific surface molecules, gp82 and gp90, play determinant roles in target cell invasion in vitro and in ora...
Autores principales: | Rodrigues, João Paulo Ferreira, Sant'ana, Guilherme Hideki Takahashi, Juliano, Maria Aparecida, Yoshida, Nobuko |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5563561/ https://www.ncbi.nlm.nih.gov/pubmed/28607099 http://dx.doi.org/10.1128/IAI.00302-17 |
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