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Apoptotic resistance of human skin mast cells is mediated by Mcl-1

Mast cells (MCs) are major effector cells of allergic reactions and contribute to multiple other pathophysiological processes. MCs are long-lived in the tissue microenvironment, in which they matured, but it remains ill-defined how longevity is established by the natural habitat, as research on huma...

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Detalles Bibliográficos
Autores principales: Hazzan, Tarek, Eberle, Jürgen, Worm, Margitta, Babina, Magda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5563844/
https://www.ncbi.nlm.nih.gov/pubmed/28845295
http://dx.doi.org/10.1038/cddiscovery.2017.48