In Vitro Hb Production in B-thalassemia Patients Is Not a Predictor of Clinical Responsiveness to Hydroxyurea

BACKGROUND: The hematologic response to hydroxyurea (HU) is varied among β-thalassemia (BT) patients. The BCL11A and SOX6 genes are involved in response to HU. This study aimed to investigate the in-vitro responsiveness of HU among BT major patients homozygote for IVSII-1G>A mutation and XmnI sin...

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Detalles Bibliográficos
Autores principales: MAHDAVI, Mohammad Reza, POURFARZAD, Farzin, KOSARYAN, Mehrnoush, AKBARI, Mohammad Taghi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Tehran University of Medical Sciences 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5563877/
https://www.ncbi.nlm.nih.gov/pubmed/28845406

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5563877/
https://www.ncbi.nlm.nih.gov/pubmed/28845406

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