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Accelerated atherosclerosis development in C57Bl6 mice by overexpressing AAV-mediated PCSK9 and partial carotid ligation
Studying the role of a particular gene in atherosclerosis typically requires a time-consuming and often difficult process of generating double-knockouts or transgenics on ApoE(−/−) or LDL receptor(−/−) background. Recently, it was reported that adeno-associated-virus-8 (AAV8) mediated overexpression...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5563968/ https://www.ncbi.nlm.nih.gov/pubmed/28504688 http://dx.doi.org/10.1038/labinvest.2017.47 |