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The chemistry and biology of mycolactones

Mycolactones are a group of macrolides excreted by the human pathogen Mycobacterium ulcerans, which exhibit cytotoxic, immunosuppressive and analgesic properties. As the virulence factor of M. ulcerans, mycolactones are central to the pathogenesis of the neglected disease Buruli ulcer, a chronic and...

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Detalles Bibliográficos
Autores principales: Gehringer, Matthias, Altmann, Karl-Heinz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5564285/
https://www.ncbi.nlm.nih.gov/pubmed/28904608
http://dx.doi.org/10.3762/bjoc.13.159