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The chemistry and biology of mycolactones
Mycolactones are a group of macrolides excreted by the human pathogen Mycobacterium ulcerans, which exhibit cytotoxic, immunosuppressive and analgesic properties. As the virulence factor of M. ulcerans, mycolactones are central to the pathogenesis of the neglected disease Buruli ulcer, a chronic and...
Autores principales: | Gehringer, Matthias, Altmann, Karl-Heinz |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Beilstein-Institut
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5564285/ https://www.ncbi.nlm.nih.gov/pubmed/28904608 http://dx.doi.org/10.3762/bjoc.13.159 |
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