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Ganetespib induces G2/M cell cycle arrest and apoptosis in gastric cancer cells through targeting of receptor tyrosine kinase signaling

Heat shock protein 90 (HSP90) regulates several important cellular processes via its repertoire of 'client proteins'. These client proteins have been found to play fundamental roles in signal transduction, cell proliferation, cell cycle progression and survival, as well as other features o...

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Detalles Bibliográficos
Autores principales: Lee, Harry, Saini, Nipun, Parris, Amanda B., Zhao, Ming, Yang, Xiaohe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5564404/
https://www.ncbi.nlm.nih.gov/pubmed/28713919
http://dx.doi.org/10.3892/ijo.2017.4073