A genetic polymorphism repurposes the G-protein coupled and membrane-associated estrogen receptor GPER to a transcription factor-like molecule promoting paracrine signaling between stroma and breast carcinoma cells

GPER is a membrane-associated estrogen receptor of the family of G-protein coupled receptors. For breast cancer, the contribution of GPER to promoting the proliferation and migration of both carcinoma cells and cancer-associated fibroblasts (CAFs) in response to estrogen and other agonists has exten...

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Detalles Bibliográficos
Autores principales: Pupo, Marco, Bodmer, Alexandre, Berto, Melissa, Maggiolini, Marcello, Dietrich, Pierre-Yves, Picard, Didier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Priority Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5564519/
https://www.ncbi.nlm.nih.gov/pubmed/28596490
http://dx.doi.org/10.18632/oncotarget.18156

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5564519/
https://www.ncbi.nlm.nih.gov/pubmed/28596490
http://dx.doi.org/10.18632/oncotarget.18156

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