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A genetic polymorphism repurposes the G-protein coupled and membrane-associated estrogen receptor GPER to a transcription factor-like molecule promoting paracrine signaling between stroma and breast carcinoma cells
GPER is a membrane-associated estrogen receptor of the family of G-protein coupled receptors. For breast cancer, the contribution of GPER to promoting the proliferation and migration of both carcinoma cells and cancer-associated fibroblasts (CAFs) in response to estrogen and other agonists has exten...
Autores principales: | Pupo, Marco, Bodmer, Alexandre, Berto, Melissa, Maggiolini, Marcello, Dietrich, Pierre-Yves, Picard, Didier |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5564519/ https://www.ncbi.nlm.nih.gov/pubmed/28596490 http://dx.doi.org/10.18632/oncotarget.18156 |
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