Mislocalization of centromeric histone H3 variant CENP-A contributes to chromosomal instability (CIN) in human cells

Chromosomal instability (CIN) is a hallmark of many cancers and a major contributor to tumorigenesis. Centromere and kinetochore associated proteins such as the evolutionarily conserved centromeric histone H3 variant CENP-A, associate with centromeric DNA for centromere function and chromosomal stab...

Descripción completa

Detalles Bibliográficos
Autores principales: Shrestha, Roshan L., Ahn, Grace S., Staples, Mae I., Sathyan, Kizhakke M., Karpova, Tatiana S., Foltz, Daniel R., Basrai, Munira A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper: Chromosome
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5564523/
https://www.ncbi.nlm.nih.gov/pubmed/28596481
http://dx.doi.org/10.18632/oncotarget.18108

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5564523/
https://www.ncbi.nlm.nih.gov/pubmed/28596481
http://dx.doi.org/10.18632/oncotarget.18108

Ejemplares similares