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Mislocalization of centromeric histone H3 variant CENP-A contributes to chromosomal instability (CIN) in human cells

Chromosomal instability (CIN) is a hallmark of many cancers and a major contributor to tumorigenesis. Centromere and kinetochore associated proteins such as the evolutionarily conserved centromeric histone H3 variant CENP-A, associate with centromeric DNA for centromere function and chromosomal stab...

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Detalles Bibliográficos
Autores principales:	Shrestha, Roshan L., Ahn, Grace S., Staples, Mae I., Sathyan, Kizhakke M., Karpova, Tatiana S., Foltz, Daniel R., Basrai, Munira A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Research Paper: Chromosome
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5564523/ https://www.ncbi.nlm.nih.gov/pubmed/28596481 http://dx.doi.org/10.18632/oncotarget.18108

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