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A cancer vaccine based on fluorine-modified sialyl-Tn induces robust immune responses in a murine model

Development of an effective vaccine to target tumor associated carbohydrate antigens, aberrantly expressed on the cell surface of various carcinomas, is an appealing approach toward cancer immunotherapy. However, a major problem of carbohydrate antigens is their poor immunogenicity. Immunization wit...

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Detalles Bibliográficos
Autores principales: Song, Chengcheng, Zheng, Xiu-Jing, Liu, Chang-Cheng, Zhou, Yifa, Ye, Xin-Shan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5564568/
https://www.ncbi.nlm.nih.gov/pubmed/28537884
http://dx.doi.org/10.18632/oncotarget.17646