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Effects and related mechanisms of serotonin on malignant biological behavior of hepatocellular carcinoma via regulation of Yap
5-hydroxytryptamine (5-HT, serotonin) and Yes-associated protein (Yap), which act as a mitogen and an oncogene, respectively, play an important role in tumors. Here, we investigated whether 5-HT could affect the hepatocarcinogenic process via promoting the activation and expression of Yap, as well a...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5564575/ https://www.ncbi.nlm.nih.gov/pubmed/28537892 http://dx.doi.org/10.18632/oncotarget.17658 |