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Effects and related mechanisms of serotonin on malignant biological behavior of hepatocellular carcinoma via regulation of Yap

5-hydroxytryptamine (5-HT, serotonin) and Yes-associated protein (Yap), which act as a mitogen and an oncogene, respectively, play an important role in tumors. Here, we investigated whether 5-HT could affect the hepatocarcinogenic process via promoting the activation and expression of Yap, as well a...

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Detalles Bibliográficos
Autores principales: Liu, Sushun, Miao, Runchen, Zhai, Mimi, Pang, Qing, Deng, Yan, Liu, Sinan, Qu, Kai, Liu, Chang, Zhang, Jingyao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5564575/
https://www.ncbi.nlm.nih.gov/pubmed/28537892
http://dx.doi.org/10.18632/oncotarget.17658