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Intratumoral depletion of regulatory T cells using CD25-targeted photodynamic therapy in a mouse melanoma model induces antitumoral immune responses

Tumor immunotherapy aims to overcome the immunosuppressive microenvironment within tumors, and various approaches have been developed. Tumor-associated T regulatory cells (Tregs) suppress the activation and expansion of tumor antigen-specific effector T cells, thus, providing a permissive environmen...

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Detalles Bibliográficos
Autores principales: Oh, Dong Sun, Kim, Heegon, Oh, Ji Eun, Jung, Hi Eun, Lee, Yun Soo, Park, Ji-Ho, Lee, Heung Kyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5564577/
https://www.ncbi.nlm.nih.gov/pubmed/28537894
http://dx.doi.org/10.18632/oncotarget.17663