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Intratumoral depletion of regulatory T cells using CD25-targeted photodynamic therapy in a mouse melanoma model induces antitumoral immune responses
Tumor immunotherapy aims to overcome the immunosuppressive microenvironment within tumors, and various approaches have been developed. Tumor-associated T regulatory cells (Tregs) suppress the activation and expansion of tumor antigen-specific effector T cells, thus, providing a permissive environmen...
Autores principales: | Oh, Dong Sun, Kim, Heegon, Oh, Ji Eun, Jung, Hi Eun, Lee, Yun Soo, Park, Ji-Ho, Lee, Heung Kyu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5564577/ https://www.ncbi.nlm.nih.gov/pubmed/28537894 http://dx.doi.org/10.18632/oncotarget.17663 |
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