KIR2DL5 mutation and loss underlies sporadic dermal neurofibroma pathogenesis and growth

Dermal neurofibromas (DNFs) are benign peripheral nerve sheath tumors thought to originate from Schwann cell progenitors. These tumors represent one of the hallmarks of the neurofibromatosis type 1 (NF1) tumor predisposition syndrome, where they can number in the thousands. While NF1-DNFs arise due...

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Detalles Bibliográficos
Autores principales: Anastasaki, Corina, Dahiya, Sonika, Gutmann, David H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5564588/
https://www.ncbi.nlm.nih.gov/pubmed/28548933
http://dx.doi.org/10.18632/oncotarget.17736

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5564588/
https://www.ncbi.nlm.nih.gov/pubmed/28548933
http://dx.doi.org/10.18632/oncotarget.17736

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