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KIR2DL5 mutation and loss underlies sporadic dermal neurofibroma pathogenesis and growth
Dermal neurofibromas (DNFs) are benign peripheral nerve sheath tumors thought to originate from Schwann cell progenitors. These tumors represent one of the hallmarks of the neurofibromatosis type 1 (NF1) tumor predisposition syndrome, where they can number in the thousands. While NF1-DNFs arise due...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Impact Journals LLC
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5564588/ https://www.ncbi.nlm.nih.gov/pubmed/28548933 http://dx.doi.org/10.18632/oncotarget.17736 |