HDAC4 stimulates MRTF-A expression and drives fibrogenesis in hepatic stellate cells by targeting miR-206

Activation of hepatic stellate cells (HSCs) is a hallmark event during liver fibrogenesis. We have previously shown that the transcriptional modulator MRTF-A contributes to liver fibrosis by programming epigenetic activation of HSCs. In the present study we investigated the mechanism whereby MRTF-A...

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Detalles Bibliográficos
Autores principales: Han, Xinrui, Hao, Chenzhi, Li, Luyang, Li, Jianfei, Fang, Mingming, Zheng, Yuanlin, Lu, Jun, Li, Ping, Xu, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5564589/
https://www.ncbi.nlm.nih.gov/pubmed/28548935
http://dx.doi.org/10.18632/oncotarget.17739

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5564589/
https://www.ncbi.nlm.nih.gov/pubmed/28548935
http://dx.doi.org/10.18632/oncotarget.17739

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