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N-myc downstream-regulated gene 1 promotes oxaliplatin-triggered apoptosis in colorectal cancer cells via enhancing the ubiquitination of Bcl-2

N-myc downstream-regulated gene1 (NDRG1) has been identified as a potent tumor suppressor gene. The molecular mechanisms of anti-tumor activity of NDRG1 involve its suppressive effects on a variety of tumorigenic signaling pathways. The purpose of this study was to investigate the role of NDRG1 in t...

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Detalles Bibliográficos
Autores principales: Yang, Xiao, Zhu, Fan, Yu, Chaoran, Lu, Jiaoyang, Zhang, Luyang, Lv, Yanfeng, Sun, Jing, Zheng, Minhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5564599/
https://www.ncbi.nlm.nih.gov/pubmed/28537875
http://dx.doi.org/10.18632/oncotarget.17711