Identifying drug-pathway association pairs based on L1L2,1-integrative penalized matrix decomposition

The traditional methods of drug discovery follow the “one drug-one target” approach, which ignores the cellular and physiological environment of the action mechanism of drugs. However, pathway-based drug discovery methods can overcome this limitation. This kind of method, such as the Integrative Pen...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Dong-Qin, Gao, Ying-Lian, Liu, Jin-Xing, Zheng, Chun-Hou, Kong, Xiang-Zhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5564627/
https://www.ncbi.nlm.nih.gov/pubmed/28624800
http://dx.doi.org/10.18632/oncotarget.18254

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5564627/
https://www.ncbi.nlm.nih.gov/pubmed/28624800
http://dx.doi.org/10.18632/oncotarget.18254

Ejemplares similares