Assessment of concordance between fresh-frozen and formalin-fixed paraffin embedded tumor DNA methylation using a targeted sequencing approach

DNA methylation is altered in many types of disease, including metastatic colorectal cancer. However, the methylome has not yet been fully described in archival formalin-fixed paraffin embedded (FFPE) samples in the context of matched fresh-frozen (FF) tumor material at base-pair resolution using a...

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Detalles Bibliográficos
Autores principales: Moran, Bruce, Das, Sudipto, Smeets, Dominiek, Peutman, Gillian, Klinger, Rut, Fender, Bozena, Connor, Kate, Ebert, Matthias, Gaiser, Timo, Prehn, Jochen HM, Bacon, Orna, Kay, Elaine, Hennessy, Bryan, Murphy, Verena, Ylstra, Bauke, Lambrechts, Diether, Byrne, Annette T., Gallagher, William M., O’Connor, Darran P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5564631/
https://www.ncbi.nlm.nih.gov/pubmed/28611295
http://dx.doi.org/10.18632/oncotarget.18296

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5564631/
https://www.ncbi.nlm.nih.gov/pubmed/28611295
http://dx.doi.org/10.18632/oncotarget.18296

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