ZNF131 suppresses centrosome fragmentation in glioblastoma stem-like cells through regulation of HAUS5

Zinc finger domain genes comprise ∼3% of the human genome, yet many of their functions remain unknown. Here we investigated roles for the vertebrate-specific BTB domain zinc finger gene ZNF131 in the context of human brain tumors. We report that ZNF131 is broadly required for Glioblastoma stem-like...

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Detalles Bibliográficos
Autores principales: Ding, Yu, Herman, Jacob A., Toledo, Chad M., Lang, Jackie M., Corrin, Philip, Girard, Emily J., Basom, Ryan, Delrow, Jeffrey J., Olson, James M., Paddison, Patrick J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Priority Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5564707/
https://www.ncbi.nlm.nih.gov/pubmed/28596487
http://dx.doi.org/10.18632/oncotarget.18153

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5564707/
https://www.ncbi.nlm.nih.gov/pubmed/28596487
http://dx.doi.org/10.18632/oncotarget.18153

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