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Aging-dependent DNA hypermethylation and gene expression of GSTM1 involved in T cell differentiation

This study investigated whether aging was associated with epigenetic changes of DNA hypermethylation on immune gene expression and lymphocyte differentiation. We screened CG sites of methylation in blood leukocytes from different age populations, picked up genes with age-related increase of CG methy...

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Detalles Bibliográficos
Autores principales: Yeh, Shu-Hui, Liu, Cheng-Ling, Chang, Ren-Chieh, Wu, Chih-Chiang, Lin, Chia-Hsueh, Yang, Kuender D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5564710/
https://www.ncbi.nlm.nih.gov/pubmed/28596482
http://dx.doi.org/10.18632/oncotarget.18109