Aurora kinase B dependent phosphorylation of 53BP1 is required for resolving merotelic kinetochore-microtubule attachment errors during mitosis

Defects in resolving kinetochore-microtubule attachment mistakes during mitosis is linked to chromosome instability associated with carcinogenesis as well as resistance to cancer therapy. Here we report for the first time that tumor suppressor p53-binding protein 1 (53BP1) is phosphorylated at serin...

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Detalles Bibliográficos
Autores principales: Wang, Haibo, Peng, Bin, Pandita, Raj K., Engler, David A., Matsunami, Risë K., Xu, Xingzhi, Hegde, Pavana M., Butler, Brian E., Pandita, Tej K., Mitra, Sankar, Xu, Bo, Hegde, Muralidhar L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5564716/
https://www.ncbi.nlm.nih.gov/pubmed/28415769
http://dx.doi.org/10.18632/oncotarget.16225

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5564716/
https://www.ncbi.nlm.nih.gov/pubmed/28415769
http://dx.doi.org/10.18632/oncotarget.16225

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