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USP14 de-ubiquitinates vimentin and miR-320a modulates USP14 and vimentin to contribute to malignancy in gastric cancer cells

Vimentin plays important roles in the epithelial-to-mesenchymal transition (EMT). In this study, we found that vimentin was highly expressed in human gastric cancer (GC) tissues and cell lines and significantly promoted cell growth, migration and invasion. Ubiquitin-specific protease 14 (USP14) inte...

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Detalles Bibliográficos
Autores principales: Zhu, Ying, Zhang, Yan, Sui, Zhenhua, Zhang, Yi, Liu, Min, Tang, Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5564720/
https://www.ncbi.nlm.nih.gov/pubmed/27448976
http://dx.doi.org/10.18632/oncotarget.10706