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EMT-like circulating tumor cells in ovarian cancer patients are enriched by platinum-based chemotherapy

BACKGROUND: Assuming that tumor cell dissemination requires a shift to a mesenchymal phenotype, we analyzed the incidence of epithelial-to-mesenchymal-transition (EMT)-like circulating tumor cells (CTCs) in ovarian cancer patients and inquired, how their molecular phenotypes respond to platinum-base...

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Detalles Bibliográficos
Autores principales: Chebouti, Issam, Kasimir-Bauer, Sabine, Buderath, Paul, Wimberger, Pauline, Hauch, Siegfried, Kimmig, Rainer, Kuhlmann, Jan Dominik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5564727/
https://www.ncbi.nlm.nih.gov/pubmed/28415744
http://dx.doi.org/10.18632/oncotarget.16179