Hematopoietic stem/progenitor cells are less prone to undergo apoptosis than lymphocytes despite similar DNA damage response

Hematopoietic stem/progenitor CD34+ cells (HSPC) give rise to all types of blood cells and represent a key cellular target for origination of leukemia. Apoptosis and repair of DNA double strand breaks (DSB) are vital processes in leukemogenesis. High doses of ionizing radiation are the best known ag...

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Detalles Bibliográficos
Autores principales: Durdik, Matus, Kosik, Pavol, Kruzliakova, Jana, Jakl, Lukas, Markova, Eva, Belyaev, Igor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5564729/
https://www.ncbi.nlm.nih.gov/pubmed/28415626
http://dx.doi.org/10.18632/oncotarget.16455

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5564729/
https://www.ncbi.nlm.nih.gov/pubmed/28415626
http://dx.doi.org/10.18632/oncotarget.16455

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