The tumor suppressor interferon regulatory factor 8 inhibits β-catenin signaling in breast cancers, but is frequently silenced by promoter methylation

Interferon (IFN) regulatory factor 8 is encoded by a novel candidate tumor suppressor gene (IRF8), its promotor is frequently methylated in multiple cancers. However, the promoter methylation status, functions and underlying mechanisms of IRF8 in breast cancer remain unclear. We found that IRF8 was...

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Detalles Bibliográficos
Autores principales: Luo, Xinrong, Xiong, Xin, Shao, Qing, Xiang, Tingxiu, Li, Lili, Yin, Xuedong, Li, Xia, Tao, Qian, Ren, Guosheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5564732/
https://www.ncbi.nlm.nih.gov/pubmed/28388578
http://dx.doi.org/10.18632/oncotarget.16511

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5564732/
https://www.ncbi.nlm.nih.gov/pubmed/28388578
http://dx.doi.org/10.18632/oncotarget.16511

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