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HistoneH3 demethylase JMJD2A promotes growth of liver cancer cells through up-regulating miR372
Changes in histone lysine methylation status have been observed during cancer formation. JMJD2A protein is a demethylase that is overexpressed in several tumors. Herein, our results demonstrate that JMJD2A accelerates malignant progression of liver cancer cells in vitro and in vivo. Mechanistically,...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5564752/ https://www.ncbi.nlm.nih.gov/pubmed/28467776 http://dx.doi.org/10.18632/oncotarget.17095 |