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HistoneH3 demethylase JMJD2A promotes growth of liver cancer cells through up-regulating miR372

Changes in histone lysine methylation status have been observed during cancer formation. JMJD2A protein is a demethylase that is overexpressed in several tumors. Herein, our results demonstrate that JMJD2A accelerates malignant progression of liver cancer cells in vitro and in vivo. Mechanistically,...

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Detalles Bibliográficos
Autores principales: An, Jiahui, Xu, Jie, Li, Jiao, Jia, Song, Li, Xiaonan, Lu, Yanan, Yang, Yuxin, Lin, Zhuojia, Xin, Xiaoru, Wu, Mengying, Zheng, Qidi, Pu, Hu, Gui, Xin, Li, Tianming, Lu, Dongdong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5564752/
https://www.ncbi.nlm.nih.gov/pubmed/28467776
http://dx.doi.org/10.18632/oncotarget.17095