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Inflammatory microRNA-194 and -515 attenuate the biosynthesis of chondroitin sulfate during human intervertebral disc degeneration

Intervertebral disc degeneration (IDD) is characterized by dehydration and loss of extracellular matrixes in the nucleus pulposus region. Chondroitin sulfate has been found to be the water-binding molecule that played a key role in IDD. Although investigators have reported that inflammatory cytokine...

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Detalles Bibliográficos
Autores principales: Hu, Bo, Xu, Chen, Tian, Ye, Shi, Changgui, Zhang, Ying, Deng, Lianfu, Zhou, Hongyu, Cao, Peng, Chen, Huajiang, Yuan, Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5564769/
https://www.ncbi.nlm.nih.gov/pubmed/28514734
http://dx.doi.org/10.18632/oncotarget.17571