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Endoplasmic reticulum stress promotes autophagy and apoptosis and reverses chemoresistance in human ovarian cancer cells

Ovarian cancer presents the highest mortality rate among gynecological tumors. Here, we measured cell viability, proliferation, apoptosis, autophagy, and expression of endoplasmic reticulum stress (ERS)-related proteins, PI3K/AKT/mTOR pathway-related proteins, and apoptosis- and autophagy-related pr...

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Detalles Bibliográficos
Autores principales: Hu, Jin-Long, Hu, Xin-Long, Guo, Ai-Ye, Wang, Chao-Jie, Wen, Yi-Yang, Cang, Shun-Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5564776/
https://www.ncbi.nlm.nih.gov/pubmed/28537902
http://dx.doi.org/10.18632/oncotarget.17673