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Oroxylin A inhibits the generation of Tregs in non-small cell lung cancer

Oroxylin A (OA), a naturally occurring monoflavonoid isolated from Scutellariae radix, has previously been reported to inhibit the proliferation of several cancer cell lines. CD4(+)CD25(+)Foxp3(+) regulatory T cells (Tregs) play an important role in maintenance of immunologic self-tolerance. Tregs a...

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Detalles Bibliográficos
Autores principales: Shen, Le, Zhang, Lu-Lu, Li, Hui, Liu, Xiao, Yu, Xiao-Xuan, Hu, Po, Hui, Hui, Guo, Qing-Long, Zhang, Shuai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5564777/
https://www.ncbi.nlm.nih.gov/pubmed/28472762
http://dx.doi.org/10.18632/oncotarget.17218