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IKBKE regulates cell proliferation and epithelial–mesenchymal transition of human malignant glioma via the Hippo pathway

IKBKE is increased in several types of cancers and is associated with tumour malignancy. In this study, we confirmed that IKBKE promoted glioma proliferation, migration and invasion in vitro. Then, we further discovered that IKBKE increased Yes-associated protein 1 (YAP1) and TEA domain family membe...

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Detalles Bibliográficos
Autores principales: Lu, Jie, Yang, Yi, Guo, Gaochao, Liu, Yang, Zhang, Zhimeng, Dong, Shicai, Nan, Yang, Zhao, Zhenyi, Zhong, Yue, Huang, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5564784/
https://www.ncbi.nlm.nih.gov/pubmed/28548934
http://dx.doi.org/10.18632/oncotarget.17738