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Dietary grape seed proanthocyanidins inactivate regulatory T cells by promoting NER-dependent DNA repair in dendritic cells in UVB-exposed skin

Ultraviolet B (UVB) radiation induces regulatory T cells (Treg cells) and depletion of these Treg cells alleviates immunosuppression and inhibits photocarcinogenesis in mice. Here, we determined the effects of dietary grape seed proanthocyanidins (GSPs) on the development and activity of UVB-induced...

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Detalles Bibliográficos
Autores principales: Vaid, Mudit, Prasad, Ram, Singh, Tripti, Katiyar, Santosh K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5564793/
https://www.ncbi.nlm.nih.gov/pubmed/28548949
http://dx.doi.org/10.18632/oncotarget.17867