Assessment of GSK1904529A as a promising anti-osteosarcoma agent

The insulin growth factor-I receptor (IGF1R) signaling is a key mechanism for osteosarcoma (OS) cell proliferation. GSK1904529A is a novel small molecule IGF1R kinase inhibitor. Its activity against OS cells was tested. In both established OS cell lines (Saos-2 and MG-63) and primary human OS cells,...

Descripción completa

Detalles Bibliográficos
Autores principales: Fei, Hao-Dong, Yuan, Qi, Mao, Li, Chen, Feng-Li, Cui, Zhao-Hui, Tao, Sha, Ji, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5564795/
https://www.ncbi.nlm.nih.gov/pubmed/28572530
http://dx.doi.org/10.18632/oncotarget.17911

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5564795/
https://www.ncbi.nlm.nih.gov/pubmed/28572530
http://dx.doi.org/10.18632/oncotarget.17911

Ejemplares similares