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Assessment of GSK1904529A as a promising anti-osteosarcoma agent

The insulin growth factor-I receptor (IGF1R) signaling is a key mechanism for osteosarcoma (OS) cell proliferation. GSK1904529A is a novel small molecule IGF1R kinase inhibitor. Its activity against OS cells was tested. In both established OS cell lines (Saos-2 and MG-63) and primary human OS cells,...

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Detalles Bibliográficos
Autores principales:	Fei, Hao-Dong, Yuan, Qi, Mao, Li, Chen, Feng-Li, Cui, Zhao-Hui, Tao, Sha, Ji, Feng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5564795/ https://www.ncbi.nlm.nih.gov/pubmed/28572530 http://dx.doi.org/10.18632/oncotarget.17911

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