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Down-regulation of UBC9 increases the sensitivity of hepatocellular carcinoma to doxorubicin
UBC9 is an E2-conjugating enzyme that is required for SUMOylation and has been implicated in regulating several critical cellular pathways. UBC9 is overexpressed in certain tumors, such as lung adenocarcinoma, ovarian carcinoma and melanoma, which implies that it has special clinical significance. H...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Impact Journals LLC
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5564807/ https://www.ncbi.nlm.nih.gov/pubmed/28572537 http://dx.doi.org/10.18632/oncotarget.17939 |