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DAXX/ATRX and MEN1 genes are strong prognostic markers in pancreatic neuroendocrine tumors

BACKGROUND: PanNETs shows heterogeneous biological behaviors. The aim was to investigate prognostic markers based on most frequently mutated genes in PanNETs. RESULTS: There was a total of 76 patients (M: 39, F: 37) with pathologically proven PanNETs. ATRX/DAXX and MEN1 protein expression was detect...

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Detalles Bibliográficos
Autores principales: Park, Joo Kyung, Paik, Woo Hyun, Lee, Kyoungbun, Ryu, Ji Kon, Lee, Sang Hyub, Kim, Yong-Tae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5564808/
https://www.ncbi.nlm.nih.gov/pubmed/28591701
http://dx.doi.org/10.18632/oncotarget.17964