Poly(adenosine diphosphate-ribose) polymerase as therapeutic target: lessons learned from its inhibitors

Poly(ADP-ribose) polymerases are a family of DNA-dependent nuclear enzymes catalyzing the transfer of ADP-ribose moieties from cellular nicotinamide-adenine-dinucleotide to a variety of target proteins. Although they have been considered as resident nuclear elements of the DNA repair machinery, rece...

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Detalles Bibliográficos
Autores principales: Cseh, Anna Mária, Fábián, Zsolt, Sümegi, Balázs, Scorrano, Luca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5564845/
https://www.ncbi.nlm.nih.gov/pubmed/28430591
http://dx.doi.org/10.18632/oncotarget.16859

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5564845/
https://www.ncbi.nlm.nih.gov/pubmed/28430591
http://dx.doi.org/10.18632/oncotarget.16859

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