Niraparib in ovarian cancer: results to date and clinical potential

Ovarian cancer is the first cause of death from gynaecological malignancy. Germline mutation in BRCA1 and 2, two genes involved in the mechanisms of reparation of DNA damage, are showed to be related with the incidence of breast and ovarian cancer, both sporadic and familiar. PARP is a family of enz...

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Detalles Bibliográficos
Autores principales: Caruso, Davide, Papa, Anselmo, Tomao, Silverio, Vici, Patrizia, Panici, Pierluigi Benedetti, Tomao, Federica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2017
Materias:
Reviews
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5564880/
https://www.ncbi.nlm.nih.gov/pubmed/29081841
http://dx.doi.org/10.1177/1758834017718775

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5564880/
https://www.ncbi.nlm.nih.gov/pubmed/29081841
http://dx.doi.org/10.1177/1758834017718775

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