Determination of High-affinity Antibody-antigen Binding Kinetics Using Four Biosensor Platforms

Label-free optical biosensors are powerful tools in drug discovery for the characterization of biomolecular interactions. In this study, we describe the use of four routinely used biosensor platforms in our laboratory to evaluate the binding affinity and kinetics of ten high-affinity monoclonal anti...

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Detalles Bibliográficos
Autores principales: Yang, Danlin, Singh, Ajit, Wu, Helen, Kroe-Barrett, Rachel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MyJove Corporation 2017
Materias:
Biochemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5564993/
https://www.ncbi.nlm.nih.gov/pubmed/28448040
http://dx.doi.org/10.3791/55659

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5564993/
https://www.ncbi.nlm.nih.gov/pubmed/28448040
http://dx.doi.org/10.3791/55659

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