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Low Retinal Dehydrogenase 1 (RALDH1) Level in Prepubertal Boys with Autism Spectrum Disorder: A Possible Link to Dopamine Dysfunction?

OBJECTIVE: Retinal dehydrogenase 1 (RALDH1) is a cytosolic enzyme which acts both as a source of retinoic acid (RA) and as a detoxification enzyme. RALDH1 has key functions in the midbrain dopaminergic system, which influences motivation, cognition, and social behavior. Since dopamine has been incre...

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Detalles Bibliográficos
Autores principales: Pavăl, Denis, Rad, Florina, Rusu, Răzvan, Niculae, Alexandru-Ştefan, Colosi, Horaţiu Alexandru, Dobrescu, Iuliana, Dronca, Eleonora
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean College of Neuropsychopharmacology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5565080/
https://www.ncbi.nlm.nih.gov/pubmed/28783931
http://dx.doi.org/10.9758/cpn.2017.15.3.229