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Fibromodulin deficiency reduces collagen structural network but not glycosaminoglycan content in a syngeneic model of colon carcinoma

Tumor barrier function in carcinoma represents a major challenge to treatment and is therefore an attractive target for increasing drug delivery. Variables related to tumor barrier include aberrant blood vessels, high interstitial fluid pressure, and the composition and structure of the extracellula...

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Detalles Bibliográficos
Autores principales: Olsson, P. Olof, Kalamajski, Sebastian, Maccarana, Marco, Oldberg, Åke, Rubin, Kristofer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5565175/
https://www.ncbi.nlm.nih.gov/pubmed/28827814
http://dx.doi.org/10.1371/journal.pone.0182973