Sub-therapeutic nevirapine concentration during antiretroviral treatment initiation among children living with HIV: Implications for therapeutic drug monitoring

Nevirapine, a component of antiretroviral therapy (ART) in resource-limited settings, known for auto-induction of metabolism, is initiated at half therapeutic dose until day 14 (‘lead-in period’), and subsequently escalated to full dose. However, studies have shown that this dosing strategy based on...

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Detalles Bibliográficos
Autores principales: Gopalan, Bindu Parachalil, Mehta, Kayur, D'souza, Reena R., Rajnala, Niharika, A. K., Hemanth Kumar, Ramachandran, Geetha, Shet, Anita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5565187/
https://www.ncbi.nlm.nih.gov/pubmed/28827836
http://dx.doi.org/10.1371/journal.pone.0183080

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5565187/
https://www.ncbi.nlm.nih.gov/pubmed/28827836
http://dx.doi.org/10.1371/journal.pone.0183080

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