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Ligation of Dectin-2 with a novel microbial ligand promotes adjuvant activity for vaccination

The development of vaccines against fungi and other intracellular microbes is impeded in part by a lack of suitable adjuvants. While most current vaccines against infectious diseases preferentially induce production of antibodies, cellular immunity is essential for the resolution of fungal infection...

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Detalles Bibliográficos
Autores principales: Wang, Huafeng, Lee, Taek-Jin, Fites, Scott J., Merkhofer, Richard, Zarnowski, Robert, Brandhorst, Tristan, Galles, Kevin, Klein, Bruce, Wüthrich, Marcel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5565193/
https://www.ncbi.nlm.nih.gov/pubmed/28793349
http://dx.doi.org/10.1371/journal.ppat.1006568