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TGF-β Signaling Is Necessary and Sufficient for Pharyngeal Arch Artery Angioblast Formation

The pharyngeal arch arteries (PAAs) are transient embryonic blood vessels that mature into critical segments of the aortic arch and its branches. Although defects in PAA development cause life-threating congenital cardiovascular defects, the molecular mechanisms that orchestrate PAA morphogenesis re...

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Detalles Bibliográficos
Autores principales: Abrial, Maryline, Paffett-Lugassy, Noëlle, Jeffrey, Spencer, Jordan, Daniel, O’Loughlin, Evan, Frederick, Charles J., Burns, C. Geoffrey, Burns, Caroline E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5565225/
https://www.ncbi.nlm.nih.gov/pubmed/28746880
http://dx.doi.org/10.1016/j.celrep.2017.07.002