A novel Drosophila injury model reveals severed axons are cleared through a Draper/MMP-1 signaling cascade

Neural injury triggers swift responses from glia, including glial migration and phagocytic clearance of damaged neurons. The transcriptional programs governing these complex innate glial immune responses are still unclear. Here, we describe a novel injury assay in adult Drosophila that elicits wides...

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Detalles Bibliográficos
Autores principales: Purice, Maria D, Ray, Arpita, Münzel, Eva Jolanda, Pope, Bernard J, Park, Daniel J, Speese, Sean D, Logan, Mary A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5565368/
https://www.ncbi.nlm.nih.gov/pubmed/28825401
http://dx.doi.org/10.7554/eLife.23611

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5565368/
https://www.ncbi.nlm.nih.gov/pubmed/28825401
http://dx.doi.org/10.7554/eLife.23611

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